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Methylene Blue and Muscle Hypertrophy

Does methylene blue have an impact on human muscle size? Methylene blue has been largely established as safe to use in humans but does it have a negative effect on muscle size? This may be important as muscle is the largest metabolic organ we have and plays an important part in glucose regulation. Thus, muscle mass plays a role in keeping glucose and insulin levels in check which keeps us insulin sensitive. Study:  Prostaglandin and myokine involvement in the cyclooxygenase-inhibiting drug enhancement of skeletal muscle adaptations to resistance exercise in older adults,  PMID: 23220477 This study look at the effect of taking paracetamol or ibuprofen while resistance training in an elderly population. They found that the drugs (common anti-inflammatories) actually promoted muscle mass and strength gains. "The drug-induced suppression of intramuscular PGE2 production increased net muscle protein balance after each exercise bout through a reduction in PGE2-induced IL-6 and ...
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Is white rice good for you?

 M any have claimed that white rice is bad for you including the well-renowned Dr David Sinclair. I agree with many of his views, including that fasting may be the single biggest thing you can do to improve your health - others such as Dr Layne Norton disagree with this and maintain caloric restriction provides equivalent benefits. In either case, your health will improve. On to the claim that white rice is bad for you! Is it true? If this claim were true then the 10,000+ years of white rice ingestion by Asian cultures would surely have lead to chronic disease and obesity. This is not what we have seen. These cultures remained healthy, lean and free of the ‘diseases of modern civilisation’. Context is important in diet and it is inappropriate to point the finger in such a way without it. The epidemiology (which can be a very weak and poor argument in many situations) does not support the theory that white rice is a problem given the 10,000 years of relative health that thes...
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